We present ALMA Band 3 data of carbon-chain species, and oxygen (O)-bearing and nitrogen(N)-bearing complex organic molecules (COMs) toward five massive young stellar objects (MYSOs). Lines of HC5N and N-bearing COMs have been detected from three MYSOs. The HC5N emission comes from hot core regions, as well as COMs. We compare observed molecular abundances to results of chemical simulations, and find that the observed abundances of COMs and HC5N can be reproduced at the hot-core stage when the temperature reaches 200 K. At this stage, the HC5N molecules, which are formed in the gas phase and accumulated in ice mantles during the prestellar and warm-up stages, sublimate from dust grains. This is a new type of carbon-chain chemistry occurring in hot regions. We also find that the MYSOs detected in HC5N and N-bearing COMs are associated with extended hot or warm regions.